Enhanced Sensitivity of Electrochemical Biosensor on Microfluidic Paper Based Analytical Device Using Zno/MWCNTS Nanocomposite

-, Roekmono and Hadi, Harsono and Imtihani, Hilya Nur and Muhimmah, Luthviyah Choirotul and Yuwono, Rio Akbar and Wahyuono, Ruri Agung (2019) Enhanced Sensitivity of Electrochemical Biosensor on Microfluidic Paper Based Analytical Device Using Zno/MWCNTS Nanocomposite. International Journal Drug Delivery Technology (IJDDT), 2 (9). ISSN 0975-4415

	Text 2. Enhanced Sensitivity of Electrochemical Biosensor on Microfluidic Paper Based Analytical Device.pdf Download (375kB)
	Text 2. Turnitin-Enhanced Sensitivity of Electrochemical Biosensor on Microfluidic Paper Based Analytical Device.pdf Download (2MB)
	Text HASIL PEER REVIEW ARTIKEL 2.pdf Download (35kB)

Official URL: http://impactfactor.org/PDF/IJDDT/9/IJDDT,Vol9,Iss...

Abstract

This paper presents an integrated ZnO/multi-walled carbon nanotubes (MWCNTs) electrode in novel stacking paper-based microfluidic analytical device for electrochemical biosensor. The designed sensors were subjected to detect glucose and ascorbic acid in a simulated body fluid using electrochemical methods, including cyclic voltammetry and impedance spectroscopy. The composite of ZnO/multi-walled carbon nanotubes (MWCNTs) with variations in mass fractions of 0.1, 0.5, 1, 2, 4 and 8% MWCNTs for measuring ascorbic acid and glucose with concentrations spanning from 0.02 to 5.12 mM. The best results are obtained by 2% of MWCNTs in composited electrode, in which linear characteristics (R2>0.8) of the current response value show a sensitivity (gradient) of 0.017 and 0.085 μA/mM.cm 2 for ascorbic acid and glucose measurement, respectively. The electrochemical detection by means of impedance spectra shows a linearly decreasing trend of chemical capacitance with increasing concentration of glucose and ascorbic acid. However, in the present system it is not sufficient to specifically distinguish the frequency response associated to glucose and ascorbic acid. Keywords: Glucose; Ascorbic Acid; ZnO; MWCNTs; Cyclic Voltammetry, Impedance Spectroscopy

Item Type:	Article
Subjects:	Kesehatan > Farmasi > Kimia Farmasi Kesehatan > Farmasi
Depositing User:	Elvia Ikasari
Date Deposited:	30 Dec 2020 05:02
Last Modified:	30 Dec 2020 05:02
URI:	http://repository.akfarsurabaya.ac.id/id/eprint/305

Actions (login required)

View Item